ESMO confress 2025 演題レポート 17-21 Oct. 2025

2025年10月17日~21日にドイツ・ベルリンで開催された 2025年 欧州臨床腫瘍学会学術集会(ESMO Congress 2025)より、食道癌や胃癌などの上部消化管癌の注目演題のレポートをお届けします。演題レポートの冒頭には、臨床研究の第一線で活躍する監修ドクターのコメントを掲載します。

演題レポート

Presidential Symposium

#LBA10
胃癌
食道胃接合部癌

Bemarituzumab (BEMA) plus chemotherapy for advanced or metastatic FGFR2b-overexpressing gastric or gastroesophageal junction cancer (G/GEJC): FORTITUDE-101 phase 3 study results

Sun Young Rha, et al.

Proffered Paper Session

#LBA79
食道癌

Lenvatinib plus Pembrolizumab and Chemotherapy vs Pembrolizumab and Chemotherapy in Untreated Metastatic Esophageal Squamous Cell Carcinoma: The Randomized Phase 3 LEAP-014 Study

Jong-Mu Sun, et al.

#LBA81
胃癌
食道胃接合部癌

Final overall survival and the association of pathological outcomes with event-free survival in MATTERHORN: a randomised, Phase 3 study of durvalumab plus 5-fluorouracil, leucovorin, oxaliplatin and docetaxel in resectable gastric / gastroesophageal junction adenocarcinoma

Josep Tabernero, et al.

#2094O
食道癌

SKYSCRAPER-07: A phase III, randomised study of atezolizumab with or without tiragolumab in patients with unresectable esophageal squamous cell carcinoma that has not progressed following definitive concurrent chemoradiotherapy

Ian Chau, et al.

Mini Oral Session

#2095MO
食道胃接合部癌

Pembrolizumab and trastuzumab in combination with FLOT in the perioperative treatment of HER2-positive localized esophagogastric adenocarcinoma: Interim analysis of the phase II PHERFLOT/IKF-053 trial of the AIO study group (AIO STO 0321)

Joseph Tintelnot, et al.